您的位置: 首页 > 农业专利 > 详情页

BIODEGRADABLE LIPIDS FOR DELIVERY OF NUCLEIC ACIDS
专利权人:
Translate Bio; Inc.
发明人:
Frank DeRosa,Michael Heartlein
申请号:
US16692846
公开号:
US20200222558A1
申请日:
2019.11.22
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention provides, in part, a biodegradable compound of formula I, and sub-formulas thereof:Formula (I) or a pharmaceutically acceptable salt thereof, where each X independently is O or S, each Y independently is O or S, and each R1 independently is defined herein; and a liposome composition comprising the cationic lipid of formula I or a sub-formula thereof, and methods of delivering agents, such as nucleic acids including mRNA, in vivo, by administering to a subject the liposome comprising the cationic lipid of formula I or a sub-formula thereof, where the agent is encapsulated within the liposome.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充