Daniel Galtier;Jean-Michel Altenburger;Frédéric Petit;Valérie Fossey
发明人:
Jean-Michel Altenburger,Valérie Fossey,Daniel Galtier,Frédéric Petit
申请号：
US12851941
公开号：
US08466292B2
申请日:
2010.08.06
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention is directed to compounds of the general formula:as well as pharmaceutical compositions thereof. The invention is also directed to their therapeutic use as urotensin II receptor antagonists, e.g., in the treatment of cardiac, coronary, and central nervous system disorders. In particular embodiments, the invention relates to 5,6-bisaryl-2-pyridinecarboxamides, to their preparation and to their therapeutic use as urotensin II receptor antagonists.
