PFEIFER, ANDREA,MUHS, ANDREAS,WATTS, RYAN,PIHLGREN, MARIA,PFEIFER, Andrea,MUHS, Andreas,WATTS, Ryan,PIHLGREN, Maria
申请号：
RSP20140084
公开号：
RS53174B
申请日:
2008.10.03
申请国别(地区):
RS
年份:
2014
代理人:
摘要：
The present invention provides novel methods and compositions comprising highly specific and highly effective antibodies that specifically recognize and bind to specific epitopes from a range of ²-amyloid proteins. The antibodies of the present invention are particularly useful for the treatment of ocular diseases associated with pathological abnormalities/changes in the tissues of the visual system, particularly those ocular diseases associated with amyloid-beta-related pathological abnormalities/changes in the tissues of the visual system.Farmaceutska supstanca za upotrebu u lečenju glaukoma, optičkog neuritisa, ili distrofija rešetkaste opne koja obuhvata terapijski delotvornu količinu monoklonskog antitela ili njegovog funkcionalnog dela, koja prepoznaje i vezuje na β-amiloidni protein, koji obuhvata lak lanac CDR1 koji ima sekvencu amino kiseline ID BR SEK: 9； laki lanac CDR2 sa sekvencom amino kiseline ID BR SEK: 10； laki lanac CDR3 sa sekvencom amino kiseline ID BR SEK: 11； teški lanac CDR1 sa sekvencom amino kiseline ID BR SEK: 12； teški lanac CDR2 sa sekvencom amino kiseline ID BR SEK: 13； teški lanac CDR3 sa sekvencom amino kiseline ID BR SEK: 14.Prijava sadrži još 25 patentnih zahteva.
