M. Stephen Trent,Brittany Needham,David Giles,Marvin Whiteley
申请号:
US13780805
公开号:
US08945587B2
申请日:
2013.02.28
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present disclosure generally relates to genetic engineering of bacteria. More particularly, the present disclosure relates to genetic engineering of Gram-negative bacteria expressing different species of lipid A on their surface. In one embodiment, the present disclosure provides for an engineered strain of E. coli according to Table 1. In another embodiment, the present disclosure provides for a lipopolysaccharide purified from an engineered strain of E. coli according to Table 1.