Dena LYRAS,Melanie HUTTON,Bliss CUNNINGHAM,Lucy LI,Glen CARTER,Julian ROOD
申请号：
US14785527
公开号：
US20160083457A1
申请日:
2014.04.17
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention relates to methods and compositions for the treatment and/or prophylaxis of Clostridium difficile associated disease (CD AD). In particular, the invention relates to antibodies that bind to C. difficile antigens and are capable of inhibiting C. difficile infection, at least one symptom of C. difficile associated disease, shedding of C. difficile, and C. difficile associated mortality. The compositions of the present application comprise: mammalian or avian antibodies which bind to a C. difficile Toxin B； and mammalian or avian antibodies that bind to a C. difficile vegetative cell antigen and/or a C. difficile endospore antigen.
