The present invention relates to antibodies to proprotein convertase subtilisin/kexin type 9 (PCSK9), or antigen-binding fragments thereof, compositions comprising such PCSK9 antibodies or antigen-binding fragments, and methods of using the same for the treatment of hyperlipidemia or hypercholesterolemia.本發明係關於原蛋白(proprotein)轉化酶枯草桿菌蛋白酶/kexin 9型(PCSK9)抗體或其抗原結合片段、包含該等PCSK9抗體或抗原結合片段之組合物,及使用其治療高脂血症或高膽固醇血症之方法。