FRASER, CHRISTOPHER,KISHIMOTO, TAKASHI KEI,MALDONADO, ROBERTO A.
申请号:
CA2834599
公开号:
CA2834599A1
申请日:
2012.04.27
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
Disclosed are synthetic nanocarrier methods, and related compositions, comprising administering immunosuppressants and MHC Class I-restricted and/or MHC Class II- restricted epitopes that can generate tolerogenic immune responses (e.g., antigen- specific T effector cell deletion).