Method of manufacturing a capsule (12) to contain a substance (14, 130), the method including the steps of: providing a first portion (2) of flexible material capsule to contain the substance (14), the first portion having (2) of capsule a closed end (5) and an opposite open end (6); providing a second portion (4) of capsule of flexible material having a closed end (7) and an opposite open end (8); at least partially filling the first portion (2) of the capsule with the substance (14); and inserting the closed end (7) of the second capsule portion (4) into the open end (6) of the first capsule portion (2) until the areas of the capsule portions (2, 4) overlap between yes, thereby closing the open end (6) of the first capsule portion (2) and forming a chamber (104) within which the substance (14) is contained, characterized in that the method includes supporting at least part of an outer side (43) of the first capsule portion (2) and supporting at least part of an inner side (102) of the second capsule portion (4), in the overlapping areas of the portions (2, 4) of capsule, while the closed end (7) of the second capsule portion (4) is inserted into the open end (6) of the first capsule portion (2).Método de fabricación de una cápsula (12) para contener una sustancia (14, 130), incluyendo el método las etapas de: proporcionar una primera porción (2) de cápsula de material flexible para contener la sustancia (14), teniendo la primera porción (2) de cápsula un extremo (5) cerrado y un extremo (6) abierto opuesto; proporcionar una segunda porción (4) de cápsula de material flexible que tiene un extremo (7) cerrado y un extremo (8) abierto opuesto; llenar al menos parcialmente la primera porción (2) de cápsula con la sustancia (14); e insertar el extremo (7) cerrado de la segunda porción (4) de cápsula en el extremo (6) abierto de la primera porción (2) de cápsula hasta que las zonas de las porciones (2, 4) de cápsula se solapen entre sí, cerrando de ese modo el extremo (