抗MERTK的激活型抗體及其應用

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专利权人:

The Rockefeller University

发明人:

TAVAZOIE Sohail,HALBERG Nils,TAVAZOIE Masoud

申请号：

HK18105107.9

公开号：

HK1245807A

申请日:

2018.04.19

申请国别(地区):

HK

年份:

2018

代理人:

摘要：

The present disclosure provides antibodies that specifically bind to Mer Tyrosine Kinase (MERTK) (e.g., human MERTK, or both human and mouse MERTK) and compositions comprising such antibodies, wherein said antibody agonizes MERTK signaling on endothelial cells. The present disclosure also provides methods for treating cancer, by administering an antibody that specifically binds to MERTK and agonizes MERTK signaling on endothelial cells.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/