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Nanoparticles for controlling bleeding and drug delivery
专利权人:
发明人:
LAVIK ERIN,SHOFFSTALL ANDREW,USTIN JEFFREY
申请号:
IN3546/DELNP/2014
公开号:
IN2014DN03546A
申请日:
2014.05.01
申请国别(地区):
IN
年份:
2015
代理人:
摘要:
A temperature stable nanoparticle is provided comprising a core a water soluble polymer and a peptide the water soluble polymer attached to the core at a first terminus of the water soluble polymer the peptide attached to a second terminus of the water soluble polymer the peptide comprising an RGD amino acid sequence the water soluble polymer of having sufficient length to allow binding of the peptide to glycoprotein lib/Ilia (GPIIb/llla). In one aspect the nanoparticle has a melting temperature over 35°C. In various aspects the nanoparticle has a spheroid shape and a diameter of less than 1 micron.
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