CONTROLLED RELEASED CARVEDIOLOL FORMULATION

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专利权人:

TSH BIOPHARM CORPORATION LTD.;INNOPHARMAX, INC.

发明人:

HAO, WEI-HUA,LIN, TSUNG-HSIN,LV, TA-CHIEN

申请号：

MYPI 2012001433

公开号：

MY157299A

申请日:

2010.09.29

申请国别(地区):

MY

年份:

2016

代理人:

摘要：

A CONTROLLED RELEASE CARVEDILOL FORMULATION FOR LESS FREQUENT, PREFERABLY ONCE DAILY ADMINISTRATION IS DESCRIBED. THE CONTROLLED RELEASE FORMULATION COMPRISES A THERAPEUTICALLY EFFECTIVE AMOUNT OF CARVEDILOL OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, A MATRIX FORMING POLYMER, A SOLUBILITY ENHANCER AND A PHARMACEUTICALLY ACCEPTABLE CARRIER. IN ONE EMBODIMENT, A CONTROLLED RELEASE FORMULATION HAVING A THERAPEUTICALLY EFFECTIVE AMOUNT OF CARVEDILOL IS CONTAINED IN TWO OR MORE SUBUNITS HAVING DIFFERENT RELEASE PROFILES. THE CONTROLLED RELEASE FORMULATION IS USABLE IN THE TREATMENT AND/OR PROPHYLAXIS OF ONE OR MORE CONDITIONS SUCH AS CARDIOVASCULAR DISORDERS. FIG. 8

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