Jennifer Leslie HARRIS,Peter GERGELY,Jun LIU,Eric SVENSSON
申请号：
US16311366
公开号：
US20200306244A1
申请日:
2017.06.20
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present disclosure relates to a Wingless-type (wnt) inhibitor of formula (I) for use in the treatment of fibrosis and some fibrosis mediated disorders such as stiff skin syndrome and systemic sclerosis. The present disclosure also provides a method for the treatment of fibrosis, a pharmaceutical combination comprising a wnt inhibitor of formula (I) and a second active ingredient for use in the treatment of fibrosis and also the use of a wnt inhibitor of formula (I) or a pharmaceutically acceptable salt thereof for the manufacture of a medicament for the treatment of fibrosis and fibrosis mediated disorders.
