James J. Moon,Rui Kuai,Anna A. Schwendeman,Jutaek Nam
申请号:
US15561374
公开号:
US20180078625A1
申请日:
2016.03.25
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to nanoparticles complexed with biomacromolecule agents configured for treating, preventing or ameliorating various types of disorders, and methods of synthesizing the same. In particular, the present invention is directed to compositions comprising nanoparticles (e.g., synthetic high density lipoprotein (sHDL)) carrying biomacromolecule agents (e.g., nucleic acid, peptides, glycolipids, etc.), methods for synthesizing such nanoparticles, as well as systems and methods utilizing such nanoparticles (e.g., in diagnostic and/or therapeutic settings).