The present invention concerns capsule endomicroscope having a predetermined axial length and a diameter being smaller than the axial length the capsule endomicroscope being adapted to acquire images of a surface of a hollow organ, comprising a microscopic image acquisition assembly the optical axis thereof is orientated into the radial direction of the capsule endomicroscope in a way to acquire microscopic images of a section of the surface of a hollow organ present in a predetermined image acquisition area on an radial outer surface of the capsule endomicroscope through a housing of the capsule endomicroscope consisting of at least sectionally light-transparent material, and a light source adapted to emit light rays in the radial direction of the capsule endomicroscope through the light-transparent material of the housing during image acquisition, wherein the light source and the light-transparent material of the housing located between the light source and the predetermined image acquisition area are interconnected to each other such that no refraction interface exists between the light source and the predetermined image acquisition area.