Combination of an HMG-CoA reductase inhibitor and a farnesyl pyrophosphatase synthase inhibitor for the treatment of diseases related to the persistence and / or accumulation of pre-packed proteins
UNIVERSITÉ D'AIX-MARSEILLE;ASSOCIATION FRANCAISE CONTRE LES MYOPATHIES (AFM);ASSISTANCE PUBLIQUE HÔPITAUX DE MARSEILLE;UNIVERSIDAD DE OVIEDO
发明人:
LEVY, NICOLAS,CAU, PIERRE,LOPEZ-OTIN, CARLOS
申请号：
ES07803849
公开号：
ES2543719T3
申请日:
2007.07.05
申请国别(地区):
ES
年份:
2015
代理人:
摘要：
Composition comprising a hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor and a farnesyl pyrophosphate synthase inhibitor, or one of its physiologically acceptable salts, for use in the treatment of pathological conditions selected from the group comprising the impairment of the vascular endothelium, progeria and restrictive dermopathy.Composición que comprende un inhibidor de hidroximetilglutaril-coenzima A (HMG-CoA) reductasa y un inhibidor de farnesil-pirofosfato sintasa, o una de sus sales fisiológicamente aceptables, para su uso en el tratamiento de afecciones patológicas seleccionadas entre el grupo que comprende el deterioro del endotelio vascular, progeria y dermopatía restrictiva.
