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PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF NON-ALCOHOLIC FAT HEPATOSIS AND METHOD FOR PREVENTING OR TREATMENT OF NON-ALCOHOLIC FATTY HEPATOSIS USING IT
专利权人:
ДОНГ-А ФАРМ. КО.; ЛТД. (KR)
发明人:
АН Гоок-Дзун (KR),ЯНГ Еун-Киоунг (KR),ЧО Еун-Дзунг (KR),ЧАЕ Ю-На (KR),ЧОИ Сонг-Хиен (KR),КИМ Ха-Донг (KR),ШИН Чанг-Йелл (KR),КИМ Ми-Киунг (KR),КВАК Воо-Янг (KR),КИМ Хеунг-Дзае (KR),СОН Моон-Хо (KR),КИ
申请号:
RU2012145116/15
公开号:
RU2012145116A
申请日:
2011.03.23
申请国别(地区):
RU
年份:
2014
代理人:
摘要:
1. A pharmaceutical composition for the prevention or treatment of non-alcoholic fatty hepatosis, comprising an active ingredient selected from the group consisting of compound 1 represented by formula 1, sitagliptin, vildagliptin, linagliptin or their pharmaceutically acceptable salts [Formula 1] 2. The composition of claim 1, wherein the active ingredient is compound 1 represented by formula 1, or a pharmaceutically acceptable salt thereof. The composition of claim 2, wherein the active ingredient is tartrate of compound 1.4. The composition of claim 1, wherein the active ingredient is sitagliptin or a pharmaceutically acceptable salt thereof. The composition of claim 4, wherein the active ingredient is sitagliptin phosphate. The composition of claim 1, wherein the active ingredient is vildagliptin or a pharmaceutically acceptable salt thereof. The composition of claim 1, wherein the active ingredient is linagliptin or a pharmaceutically acceptable salt thereof. A composition according to any one of claims 1 to 7, wherein non-alcoholic fatty hepatosis occurs as a result of hyperlipidemia, diabetes or obesity. A composition according to any one of claims 1 to 7, wherein the non-alcoholic fatty hepatosis is selected from the group consisting of simple steatosis, non-alcoholic steatohepatitis, liver fibrosis and cirrhosis of the liver. A method for preventing or treating non-alcoholic fatty hepatosis, comprising administering an effective amount of an active ingredient selected from the group consisting of compound 1 represented by formula 1, sitagliptin, vildagliptin, linagliptin or their pharmaceutically acceptable salts to a mammal, including a person in need thereof [Formula 1] eleven. The method of claim 10, wherein the active ingredient is1. Фармацевтическая композиция для предупреждения или лечения неалкогольного жирового гепатоза, включающая активный ингредиент, выбираемый из группы, состоящей из соединения 1 представленного формулой 1, ситаглиптина, вилдагли
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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