STAPHYLOCOCCUS AUREUS LEUKOCIDINS, THERAPEUTIC COMPOSITIONS, AND USES THEREOF

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专利权人:

NEW YORK UNIVERSITY

发明人:

TORRES, VICTOR J.,DUMONT, ASHLEY L.

申请号：

MYPI 2012004840

公开号：

MY165618A

申请日:

2011.05.05

申请国别(地区):

MY

年份:

2018

代理人:

摘要：

DISCLOSED HEREIN ARE ISOLATED AND PURIFIED STAPHYLOCOCCUS AUREUS BI-COMPONENT LEUCOCIDIN, REFERRED TO HEREIN AS LUKAB, AND ITS COMPONENTS LUKA AND LUKB, ANTIBODIES SPECIFIC TO LUKA, ANTIBODIES SPECIFIC TO LUKB, THERAPEUTIC COMPOSITIONS CONTAINING LUKA AND/OR LUKB, OR ANTI-LUKA AND/OR ANTI-LUKB ANTIBODIES, USES OF THE COMPOSITIONS TO TREAT ACUTE INFLAMMATORY CONDITIONS OR S. AUREUS INFECTION, METHODS FOR IDENTIFYING INHIBITORS OF LUKAB-MEDIATED CYTOTOXICITY OF HUMAN PHAGOCYTES, AND METHODS FOR USING LUKAB AS A MARKER TO PREDICT SEVERITY OF S. AUREUS INFECTION. FIGURE 1-1

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