MITCHELL SCOTT A.,CURRIE KEVIN S.,BLOMGREN PETER A.,KROPF JEFFREY E.,LEE SEUNG H.,XU JIANJUN,STAFFORD DOUGLAS G.,HARDING JAMES P.,BARBOSA JR. ANTONIO J.,ZHAO ZHONGDONG,ARMISTEAD DAVID M,STAFFORD DOUGL
申请号:
PL13005979
公开号:
PL2716157T3
申请日:
2009.12.07
申请国别(地区):
PL
年份:
2017
代理人:
摘要:
Certain imidazopyrazines and pharmaceutical compositions thereof are provided herein. Methods of treating patients suffering from certain diseases and disorders responsive to the inhibition of Syk activity, which comprises administering to such patients an amount of at least one chemical entity effective to reduce signs or symptoms of the disease or disorder are provided. Also provided are methods for determining the presence or absence of Syk kinase in a sample.