Cyclic peptidomimetic compounds as immunomodulators

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专利权人:

Pottayil Govindan Nair Sasikumar

发明人:

Pottayil Govindan Nair Sasikumar,Muralidhara Ramachandra,Seetharamaiah Setty Sudarshan Naremaddepalli

申请号：

US15332805

公开号：

US10106581B2

申请日:

2016.10.24

申请国别(地区):

US

年份:

2018

代理人:

摘要：

Methods of making a compound according to the following scheme:wherein:R1 is a side chain of an amino acid residue selected from Ala, Ser, Thr and LeuR2 is a side chain of an amino acid residue selected from Asp, Glu, Gln and Asn[Aaa] is an amino acid residue selected from Ser, Asp, Ala, Ile, Phe, Trp, Lys, Glu and ThrR3 is hydrogen or alkylEach of R4 and R4′ independently is hydrogen or alkylBoth Ra and Ra′ are hydrogen or together are an oxo(═O) groupBoth Rb and Rb′ are hydrogen or together are an oxo (═O) groupL isX is CH2, O or S R5 is hydrogen or alkyl m is an integer from 1 to 3 and n is an integer from 2 to 20.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/