A three-dimensional transurethral ultrasound system includes a transurethral ultrasound probe, an ultrasound data processor configured to communicate with the transurethral ultrasound probe to receive ultrasound signals from the transurethral ultrasound probe and to output ultrasound imaging signals for three-dimensional ultrasound images of at least a portion of a patients prostate, and a display system configured to communicate with the ultrasound data processor to receive the ultrasound imaging signals and to render three-dimensional ultrasound images of the at least the portion of the patients prostate from the ultrasound imaging signals.