The present subject matter relates to a device for aspiration of bone marrow. The device includes a driver unit with spring, handle and clutch assembly, an outer unit with spirals and needle assembly for penetration and aspiration of bone marrow from patient"s body, an inner unit with integrated piston rod and trocar that rotates with the downward motion of the handle, thereby providing force for penetration and a connector connecting the outer unit and inner unit. The said outer unit includes a breakable sheath connecting the needle assembly and barrel for imparting protection against excessive force while insertion and for enabling disengagement of needle and preventing the device reuse. The bone marrow aspiration device has an external needle positioning element to support, firmly hold and position the device on insertion site thereby preventing slippage and sideways movement of the device. This element, also provides anatomical location of the insertion site, in this particular case, it provides the penetration location with reference to the tibial tuberosity.