RUF, SVEN,PERNERSTORFER, JOSEPH,SADOWSKI, THORSTEN,HORSTICK, GEORG,SCHREUDER, HERMAN,BUNING, CHRISTIAN,OLPP, THOMAS,SCHEIPER, BODO,WIRTH, KLAUS
申请号:
HRP20150075
公开号:
HRP20150075T1
申请日:
2015.01.20
申请国别(地区):
HR
年份:
2015
代理人:
摘要:
The present invention relates to synthesis precursors useful for the preparation of compounds of the formula I, wherein A, D, E, G, R 10 , R 30 , R 40 , R 50 and R 60 have the meanings indicated in the description, which in turn are valuable pharmaceutical active compounds. They are inhibitors of the protease cathepsin A, and are useful for the treatment of diseases such as atherosclerosis, heart failure, renal diseases, liver diseases or inflammatory diseases, for example.