FIELD: medicine.SUBSTANCE: biological tissue is exposed successively in any sequence to optical light of the first range at wave lengths 950-970 nm, optical light of the second range at wave lengths 1020-1060 nm, optical light of the third range at wave lengths 930-950 nm, optical light of the fourth range at wave lengths 740-760 nm and optical light of the fifth range at wave lengths 830-850 nm. The optical light diffuse-reflected by the biological tissue is received and transformed into an electrical signal. The blood glucose concentration is determined with the use of an experimental calibration dependence of a glucose concentration and received resultant electrical signal having a value of URESULTANT = U2+U3+U5-U1(k12+k13+k15)-U4(k42+k43+k45), wherein U1, U2, U3, U4, U5 are the electrical signals received when exposing the biological tissue to the optical light of the first, second, third, fourth and fifth ranges, respectively k12, k13, k15 are coefficients derived in keeping with the expressions k12 = K2S2/K1/S1, k13 = K3S3/K1/S1, k15 = K5S5/K1/S1, wherein K1, K2, K3, K5 are average water absorption factors in the first, second, third, fourth and fifth wave length ranges, respectively S1, S2, S3, S5 are average relative spectral responses of an optical light receiver in the first, second, third, fourth and fifth wave length ranges, respectively k42, k43, k45 are coefficient pre-derived in keeping with the expressions k42 = K2S2/K4/S4, k43 = K3S3/K4/S4, k45 = K5S5/K4/S4, wherein K2, K3, K4, K5 are average water absorption factors in the first, second, third, fourth and fifth wave length ranges, respectively S2, S3, S4, S5 are average relative spectral responses of an optical light receiver in the second, third, fourth and fifth wave length ranges, respectively.EFFECT: more accurate blood glucose concentration determination by reducing a measurement uncertainty caused by presence of water and melanin in the analysed biological tissue.2 dwgИзобретение относится к
