123456Disclosed is a method for producing a compound represented by formula (I) or a salt thereof the method being characterized in that a compound represented by formula (II) or a salt thereof is reacted with an aniline derivative represented by formula (III) in water or in a mixed solvent of water and an organic solvent in the presence of 1 ethyl 3 (3 dimethylaminopropyl) carbodiimide and substantially in the absence of a base. (In the formulas R is a 4 [3 (dimethylamino)azetidin 1 yl]piperidin 1 yl group a 4 (4 methylpiperazin 1 yl)piperidin 1 yl group a 3 hydroxyazetidin 1 yl group or a methyl(1 methylpiperidin 4 yl)amino group R R R and R are each identical or different and signify a hydrogen atom or a fluorine atom and R signifies a hydrogen atom or a halogen atom.)
