Induction of the mitochondrial permeability transition

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专利权人:

NEWSOUTH INNOVATIONS PTY LIMITED

发明人:

HOGG, PHILIP JOHN

申请号：

AU2008200304

公开号：

AU2008200304B2

申请日:

2008.01.22

申请国别(地区):

AU

年份:

2012

代理人:

摘要：

INDUCTION OF THE MITOCHONDRIAL PERMEABILITY TRANSITION Abstract The present invention relates to process for identifying a compound which 5 induces the mitochondrial permeability transition (MPT) of proliferating cells, wherein said process comprises contacting a cell or cell extract with a compound, determining whether the compound binds to adenine nucleotide translocator (ANT), and determining whether the compound selectively induces the MPT in proliferating cells.

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