Dialysis and substitution fluid, designed for elimination techniques with citrate anticoagulation in the intensive care setting, wherein the fluid comprises 125 to 135 mmol/I Na, 0 to 4 mmol/l K, 0.8 to 1.8 mmol/I Mg, 110 to 125 mmol/I Cl, 0.8 to 1.2 mmol/I P, 15 to 25 mmol/I Na-lactate and 5.0 to 6.0 mmol/I glucose, where osmolality is in the range of 270 to 285 mOsm/kg.The fluid can comprise 130 mmol/l Na, 2 memol/l K, 1.5 mmol/l Mg, 116 mmol/l Cl, 1.0 mmol/l P, 18 mmol/l Na-lactate and 5.6 mmol/l glucose, where osmolality of the fluid is 274 mOsm/kg.Single chamber bag generally applicable with citrate anticoagulation that contains dialysis and substitution fluid as described above.