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用於心血管疾病和其它病況的旁分泌基因的全身性遞送和受調節的表達
专利权人:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
发明人:
HAMMOND, H., KIRK,GAO, MEI, HUA
申请号:
HK15104654.2
公开号:
HK1203845A
申请日:
2015.05.15
申请国别(地区):
HK
年份:
2015
代理人:
摘要:
In alternative embodiments, the invention provides methods for treating, ameliorating or protecting (preventing) an individual or a patient against a disease, an infection or a condition responsive to an increased paracrine polypeptide level in vivo comprising: providing a paracrine polypeptide-encoding nucleic acid or gene operatively linked to a transcriptional regulatory sequence; or an expression vehicle, a vector, a recombinant virus, or equivalent, having contained therein a paracrine-encoding nucleic acid or gene, and the expression vehicle, vector, recombinant virus, or equivalent can express the paracrine-encoding nucleic acid or gene in a cell or in vivo; and administering or delivering the paracrine polypeptide -encoding nucleic acid or gene operatively linked to a transcriptional regulatory sequence, or the expression vehicle, vector, recombinant virus, or equivalent, to an individual or a patient in need thereof, thereby treating, ameliorating or protecting (preventing) the individual or patient against the disease, infection or condition responsive to an increased paracrine polypeptide level.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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