The invention relates to a device for administering a liquid drop by drop, in particular an ophthalmic liquid. This administering device comprises a packaging filled with the liquid and an outflow channel for connecting to the packaging and comprising a perforation member at one end, which perforation member is received in a frame for mounting on the packaging. The invention further relates to an assembly of such an administering device and an outer packaging which comprises one or more receiving spaces for the administering device. The invention also relates to a method for manufacturing a frame for such an administering device. The invention also relates to a method for forming an administering device. The invention finally relates to a method for administering a liquid drop by drop.