Solomon Ungashe,John J. Wright,Andrew Pennell,Zheng Wei,Anita Melikian
申请号：
US15697414
公开号：
US20170369483A1
申请日:
2017.09.06
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Compounds are provided that act as potent antagonists of the CCR9 receptor, and which have been further confirmed in animal testing for inflammation, one of the hallmark disease states for CCR9. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR9-mediated diseases, and as controls in assays for the identification of CCR9 antagonists.
