Fibrosis, a composition for the treatment and prevention of inflammatory and neovascularization conditions and methods

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专利权人:

エルパス・インコーポレイテッド

发明人:

ロジャー・エイ・サバディニ,ウィリアム・エイ・ガーランド,グレン・エル・ストーラー

申请号：

JP2008538001

公开号：

JP5739089B2

申请日:

2006.10.27

申请国别(地区):

JP

年份:

2015

代理人:

摘要：

The present invention relates to compositions and methods for the treatment of diseases and conditions, including ocular diseases and conditions, characterized by aberrant fibrogenesis or scarring, inflammation and/or aberrant neovascularization or angiogenesis. The compositions and methods of the invention utilize immune-derived moieties that are specifically reactive against bioactive lipids and which are capable of decreasing the effective concentration of the bioactive lipids. In some embodiments, the immune-derived moiety is a monoclonal antibody that is reactive against sphinxine-1-phosphate (S1P) or lysophosphophatidic acid (LPA).

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/