A GENE THERAPY STRATEGY TO RESTORE ELECTRICAL AND CARDIAC FUNCTION, AND CARDIAC STRUCTURE, IN ARRHYTHMOGENIC RIGHT VENTRICULAR CARDIOMYOPATHY

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专利权人:

THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

发明人:

Farah Shiekh,Jing Zhang

申请号：

US16648922

公开号：

US20200215155A1

申请日:

2018.09.20

申请国别(地区):

US

年份:

2020

代理人:

摘要：

Disclosed herein are methods of treating arrhythmogenic right ventricular cardiomyopathy in a subject, comprising administering a gene therapy construct comprising a connexin 43 sequence, wherein as a result of the administration, connexin 43 levels in at least a portion of the heart are increased. Further disclosed are other cardiovascular diseases can be treated with the method.

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