The present invention is directed to devices and methods for rhythmic therapy. A system streams a patient specific audio file to a patient for therapy or rehabilitation while the patient is performing an exercise, where the audio comprises a musical track selected from a library of musical tracks, and simultaneously playing a second audio file with a motivational message, for example, and further where the tempo of the track, or the selection of the tracks are changed based on data received from sensors and determining if the patient is improving or regressing.