Michel DEMEULE,Alain LAROQUE,Gaoqiang YANG,Sasmita TRIPATHY
申请号:
US14422165
公开号:
US20160015823A1
申请日:
2013.08.14
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The invention relates to dendrimers conjugated to multiple targeting peptides and one or more therapeutic, diagnostic, or imaging agents for delivery of such agents across the blood-brain barrier and into certain cell types including, cells expressing the LRP-1 receptor. Also described are methods of making compounds that comprise dendrimers conjugated to targeting peptides and therapeutic, diagnostic, or imaging agents.