Benzisothiazole, isothiazolo[3,4-b]pyridine, quinazoline, phthalazine, pyrido[2,3-d]pyridazine and pyrido[2,3-d]pyrimidine derivatives as KRAS G12C inhibitors for treating lung, pancreatic or colorectal cancer
Lanman, Brian Alan,Cee, Victor J.,Pickrell, Alexander J.,Reed, Anthony B.,Yang, Kevin C.,Kopecky, David John,Wang, Hui-Ling,Lopez, Patricia,Ashton, Kate,Booker, Shon,Tegley, Christopher M.
申请号:
AU2017379074
公开号:
AU2017379074A1
申请日:
2017.12.21
申请国别(地区):
AU
年份:
2019
代理人:
摘要:
Provided herein are benzisothiazol, isothiazolo[3,4-b]pyridine, quinazoline, phthalazine, pyrido[2,3-d]pyridazine and pyrido[2,3-d]pyrimidine derivatives and related compounds as KRAS G12C inhibitors for treating e.g. lung cancer, pancreatic cancer or colorectal cancer.