An electro-magnetic induction device (2) for activating a target tissue in a human or animal body via its muscular or neural system comprises: (i) an electro-magnetic field generator (21) with a coil design (211) configured to generate an electro-magnetic field (212) having a targeted shape (213), (ii) a mounting arrangement (22) holding the coil design (211) of the electro-magnetic field generator (21) at the human or animal body, (iii) a sensor member (4) configured to detect an activation of the target tissue, (iv) an electro-magnetic field adjustment mechanism (21) configured to automatically adjust the position of the electro-magnetic field (212) generated by the coil design (211) and to adjust a field strength of the electro-magnetic field (212) generated by the coil design, and (v) a calibration unit (31) in communication with the sensor member (4) and with the electro-magnetic field adjustment mechanism (21). The calibration unit (31) is configured (a) to control the electro-magnetic field adjustment mechanism (21) to automatically vary the position of the electro-magnetic field (212) generated by the coil design (211) and to automatically vary the field strength of the electro-magnetic field (212) generated by the coil design, (b) to receive an activation feedback signal from the sensor member (4) upon detection of the activation of the target tissue, and (c) to control the electro-magnetic field adjustment mechanism (21) to automatically stop variation of the position of the electro-magnetic field (212) generated by the coil design (211) when the activation feedback signal is received and to automatically stop variation of the field strength of the electro-magnetic field (212) generated by the coil design (211) when the activation feedback is received.