COMPOUNDS AND METHODS FOR ALTERING LIFESPAN OF EUKARYOTIC ORGANISMS

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专利权人:

UNIVERSITY OF ROCHESTER

发明人:

GOLDFARB, DAVID, S.,MADDRY, JOSEPH, A.,RASMUSSEN, LYNN,WHITE, ELLIE, LUCILE,WENNERBERG, KRISTER

申请号：

EP10832089

公开号：

EP2501229A4

申请日:

2010.11.17

申请国别(地区):

EP

年份:

2014

代理人:

摘要：

Provided are compounds which generally have a triketone structure. Examples of the compounds include derivatives of 1,3-cyclohexanedione, such as: 1,3-cyclohexanedione, 2-propanoyl-5-cyclohexyl- 1,3-cyclohexanedione, 2-propanoyl-5-[4-fluorophenyl]- 1,3-cyclohexanedione, 2-acetyl-5-[thien-2-yl]- 1,3-cyclohexanedione, 2-acetyl-5-butyl- and 1,3-cyclohexanedione, 2-propanoyl-5-[bicyclo[2.2.1]hept-2-en-5-yl]-. The compounds can be used to alter the lifespan of eukaryotic organisms and treat inflammation.

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