Joseph D. Russo,Joseph Silvestro,James East,Mark Conway
申请号：
US14333450
公开号：
US20160015373A1
申请日:
2014.07.16
申请国别(地区):
US
年份:
2016
代理人:
摘要：
High viscosity medical adhesive formulations are provided with an applicator device that allows the medical adhesives to be easily sterilized, accurately dispensed and optimally cured for medical applications. The preferred medical adhesive formulations include 2-octyl cyanoacrylate and n-butyl-2-cyanoacrylate monomers in formulation with various additives. The medical adhesive can be formulated to be bio-absorbable and/or bio-degradable. Suitable thickeners, stabilizers, plasticizing agents, preservatives, reinforcing agents, colorants and anti-bacterial compounds may advantageously be included in the formulation. The formulation is preferably placed within a sealed aluminum or plastic tube. An applicator tip with plastic brush bristles is used for application and curing of the formulation. On one end, the applicator tip preferably has a cutting or piercing mechanism which is capable of breaking the seal on the tube. On the other end, the applicator tip brush bristles are coated and/or impregnated with a dry, solvent-free cyanoacrylate polymerization initiator and/or accelerator.
