Merck Sharp & Dohme Corp.; Inc.;Scynexis;Scynexis, Inc.
发明人:
Mamai, Ahmed,Tse, Bruno,Meng, Dongfang,Liu, Hao,Bouffard, Frances Aileen,Greenlee, Mark L.,Li, Keqaing,Balkovec, James M.,Peel, Michael,Fan, Weiming,Dropinski, James
申请号：
AU2007245024
公开号：
AU2007245024B2
申请日:
2007.03.29
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
The present invention relates to novel enfumafungin derivatives of formula I and pharmaceutically acceptable salts thereof, their synthesis, and their use as inhibitors of (l,3)-β-D-glucan synthase. The present compounds and pharmaceutically acceptable salts thereof, as well as pharmaceutical compositions comprising the present compounds and pharmaceutically acceptable salts thereof, are useful for treating or preventing antifungal infections and associated diseases and conditions.
