A composite implant includes a mesh scaffold having a biologically-active material configured to contact biological tissue and blood vessels a resin disposed on the mesh scaffold and a channel in the mesh which is configured to receive growth of the biological tissue and blood vessels, wherein the resin is biocompatible and non-absorbable. A process for preparing the composite implant includes disposing a plurality of layers of biologically-active material as an array contacting the plurality of layers with a resin and hardening the resin to form the composite implant. A process of using the composite implant includes implanting the composite implant into a subject, wherein the implant comprises: a mesh comprising a biologically-active material configured to contact biological tissue and blood vessels a resin disposed on the mesh and a channel in the mesh which is configured to receive growth of the biological tissue and blood vessels.
