您的位置: 首页 > 农业专利 > 详情页

OPTIMIZED CROSS-SPECIES SPECIFIC BISPECIFIC SINGLE CHAIN ANTIBODY CONTRUCTS
专利权人:
AMGEN RESEARCH (MUNICH) GMBH
发明人:
Benno Rattel,Matthias Friedrich,Peter Kufer,Patrick Hoffmann,Tobias Raum,Markus Münz,Ines Herrmann,Ralf Lutterbüse,Elisabeth Nahrwold
申请号:
US15329672
公开号:
US20170349668A1
申请日:
2015.07.31
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention provides to a bispecific single chain antibody construct binding to a target cell surface antigen via a first binding domain and to the T cell surface antigen CD3 via a second binding domain, wherein serum albumin is fused to the C-terminus of the antibody construct. Moreover, the invention provides a polynucleotide encoding the antibody construct, a vector comprising said polynucleotide and a host cell transformed or transfected with said vector. Furthermore, the invention provides a process for the production of the antibody construct of the invention, a medical use of said antibody construct and a kit comprising said antibody construct.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
相关发明人
相关专利

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充