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Novel crystalline forms of a dipeptidyl peptidase-IV inhibitor
专利权人:
Merck Sharp & Dohme Corp.;Merck Sharpe & Dohme Ltd.
发明人:
Arroyo, Itzia,Krueger, Davida,Chen, Ping,Moment, Aaron,Biftu, Tesfaye,Sheen, Faye,Zhang, Yanfeng
申请号:
AU2012275637
公开号:
AU2012275637B2
申请日:
2012.06.25
申请国别(地区):
AU
年份:
2016
代理人:
摘要:
Novel crystalline forms of (2R,3S,5R)-2-(2,5-Difluorophenyl)-5-[2-(methylsulfonyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl]tetrahydro-2H-pyran-3-amine are potent inhibitors of dipeptidyl peptidase-IV and are useful for the treatment of non-insulin dependent (Type 2) diabetes mellitus. The invention also relates to pharmaceutical compositions containing these novel forms, processes to prepare these forms and their pharmaceutical compositions as well as uses thereof for the treatment of Type 2 diabetes.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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