Dorange, Ismet,Bonfanti, Jean-Francois,Fortin, Jerome Michel Claude
申请号：
AU2006224533
公开号：
AU2006224533B9
申请日:
2006.03.17
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
Novel 1,3-dihydro-benzimidazo l-2-ylidene amine derivatives of formula (I)the addition salts and stereochemically iso meric forms wherein each Alk is Calkanediyl；Q is hydrogen； Calkyl subst ituted with one or two Arradicals； C6alkyl subst ituted with quinolinyl, oxazolidinyl,thiazolidinyl, morpholinyl, thiomorpholinyl, or with pyrrolidinonyl； -CO-Ar；or Q is a radical of formula wherein t is 1, 2 or 3； R is amino, mono-ordi(Calkyl)amino ； R is Ar, -CO-Aror a monocyclic or bicyclic heterocycle which may optionally be subst ituted；R is as R and additionally can be hydrogen； where Q is otherthan hydrogen, R is hydrogen； and where Q is other than hydrogen, Ris a radical: (b) wherein R is hydrogen, Calkyl, substitutedCalkyl； R, R, R are halo, cyano,Calkyl, substituted Calkyl, Calkenyl,cyanoCalkenyl, Calkynyl, cyanoCalkynyl,Ar1, R-O-, R-S-, -N(RR),R-O-C(=O)-, N(RR)-C(=O)-, R-C(=O)-NR-,R-C(=O)-O-； and Rand/or R may also be hydrogen；which are RSV inhibitors. Compositions containing these compounds and processesfor preparing these compounds and compositions.
