Christiane Dresch,Bruna de Andrade Pereira,Mathias Ackermann,Cornel Fraefel
申请号:
US14347439
公开号:
US20140242037A1
申请日:
2012.09.26
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The invention relates to transgene expression constructs—particularly self inactivating lentiviral vectors—comprising a dendritic cell specific promoter controlling the expression of autoantigen proteins, namely myelin basic protein, proteolipid protein and myelin oligodendrocyte glycoprotein, for use in the therapy of multiple sclerosis.