The invention relates to a syringe (10), preferably a single-fill syringe, for multi-component materials, comprising a mixer housing (12), a mixing element (14), a multi-component cartridge (18) and a mixing head (16), the mixing head (16) being arranged at least partly within the mixer housing (12) and adjacent to the multi-component cartridge (18), wherein the mixing head (16) is arranged moveable in an axial direction of the syringe (10) between at least two positions, the at least two positions comprising a sealed position and a dispensing position, wherein the axial movement of the mixing head (16) is brought about by a rotation of at least a part of the mixer housing (12; 12b) relative to the multi-component cartridge (18).