PROBLEM TO BE SOLVED: To provide an effective screening means in developing a medical drug effective in treating frequent micturition or urinary incontinence which an increasing number of patients suffer from.SOLUTION: There is provided a method for preparing a pelvic congestion model rat, in which a female rat whose common iliac veins on both sides and uterus vein are litigated is bred for four or more weeks. There is provided a pelvic congestion model rat obtained in the preparation method. There is provided a method for screening a drug for treating frequent micturition by using the model rat.COPYRIGHT: (C)2014,JPO&INPIT【課題】 患者が増加しつつある頻尿や尿失禁の治療に有効な医薬を開発するに当たり、有効なスクリーニング手段を提供すること。【解決手段】 メスラットの両側総腸骨静脈と子宮静脈を結紮し、4週以上飼育することを特徴とする骨盤うっ血モデルラットの作製方法、当該作製方法により得られる骨盤うっ血モデルラットおよびこのモデルラットを用いた頻尿治療薬のスクリーニング方法。【選択図】 なし
