KANG, HYUN SEO,姜显瑞,姜顯瑞,KIM, HYOUNG JUNE,金亨俊,YOO, SE JIN,刘世眞,劉世眞,KIM, JI HYUN,金知贤,金知賢
申请号：
TW104139964
公开号：
TW201628614A
申请日:
2015.11.30
申请国别(地区):
TW
年份:
2016
代理人:
摘要：
Disclosed is a composition for activating one or more genes of an XPD gene, a Klotho gene, a Sirt-1 gene, an ERCC8 gene and a FoxO3 gene, which contains a methylated catechin, a salt thereof, a prodrug thereof, a hydrate thereof, a solvate thereof or an isomer thereof as an active ingredient. In an aspect, the present disclosure provides a pharmaceutical composition, a cosmetic composition or a food composition which activates one or more genes of an XPD gene, a Klotho gene, a Sirt-1 gene, an ERCC8 gene and a FoxO3 gene and is useful in preventing or treating disease related with the genes, preventing aging and improving skin.本案揭示一種用於活化XPD基因、Klotho基因、Sirt-1基因、ERCC8基因以及FoxO3基因中之一或多種基因之組合物，其含有作為活性成分的甲基化兒茶素、其鹽、其前藥、其水合物、其溶劑合物或其異構物。在一態樣中，本發明提供活化XPD基因、Klotho基因、Sirt-1基因、ERCC8基因以及FoxO3基因中的一或多種基因且適用於預防或治療與該等基因相關之疾病、預防老化且改善皮膚之醫藥組合物、化妝品組合物或食品組合物。
