NARAIN, NIVEN RAJIN,SARANGARAJAN, RANGAPRASAD,JIMENEZ, JOAQUIN J.
申请号：
CA3026495
公开号：
CA3026495A1
申请日:
2017.06.05
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
The invention provides methods and pharmaceutical compositions for preventing or mitigating chemotherapy-induced alopecia (CIA). The pharmaceutical compositions of the invention comprise an effective amount of a vitamin D compound in a topical formulation. The invention has broad applications in chemotherapies that induce alopecia, for example taxane based chemotherapy for cervical cancer, endometrial cancer, ovarian cancer, fallopian tube cancer, primary peritoneal carcinoma, soft tissue sarcoma, or bone sarcoma. The pharmaceutical compositions of the invention can be advantageously administered before and/or concurrent with the chemotherapy.
