PROBLEM TO BE SOLVED: To provide a pharmaceutical composition that forms a molecule assembly to express viscoelasticity even when the concentration of glycyrrhizinic acid or a salt thereof is 0.3 W/V% or less and the pH of the composition is 3.0 or more.SOLUTION: A pharmaceutical composition contains (A) at least one selected from glycyrrhizinic acid and glycyrrhizinic acid salt of 0.1-0.3 W/V%, and (B) a basic substance having a cyclic structure or a polycyclic structure of 0.005-0.15 W/V%, with a mass content ratio represented by (B)/(A) of 0.017-0.6, and the pH of the composition being 3.0-6.0.SELECTED DRAWING: Figure 1COPYRIGHT: (C)2018,JPO&INPIT【課題】グリチルリチン酸又はその塩の濃度が0.3W/V%以下、pH3.0以上であっても、粘弾性を発現する分子集合体を形成する医薬組成物を提供する。【解決手段】(A)グリチルリチン酸及びグリチルリチン酸塩から選ばれる1種以上0.1~0.3W/V%、(B)環式構造又は多環式構造を有する塩基性物質0.005~0.15W/V%を含有し、(B)/(A)で表される含有質量比が0.017~0.6であり、pHが3.0~6.0の医薬組成物。【選択図】図1