A system and method for defining a cause and effect matrix (CEM) within a process control system for a process plant, including accessing a cause and effect matrix (CEM) having a set of causes and a set of effects, N wherein each of the set of causes represents a condition within the process plant and each of the set of effects represents an effect to be performed within the process plant. The system and method further includes, for each of the set of effects: (i) identifying a subset of the set of causes according to a corresponding set of the cause-effect pairs corresponding to the effect of the set of effects, (ii) defining the subset of the set of causes as a single-dimension matrix, and (iii) automatically calculating a numerical representation for the single-dimension matrix. The system and method further includes configuring a set of function blocks for the process control system according to the set of numerical representations.