The present bone screws—;and kits and methods utilizing such bone screws—;provide enhanced fatigue resistance (EFR), increased fixation strength, and/or improved tactile feedback. The enhanced fatigue resistance can increase the working life of a bone screw and reduce the possibility of a bone screw cracking or breaking and possible adverse implications thereof. The improved tactile feedback can improve usability by maintaining a level friction and resistance (during insertion of the screws into bone) that is familiar to health care providers. The present bone screws, kits, and methods may be configured and/or implemented for use in the repair of cancellous and/or cortical bone.